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The question as to whether cardiac myocytes per se can release inflammatory mediators and assume a pro-inflammatory phenotype has already been answered by a number of investigators, who demonstrated the inducible release of many growth and inflammatory factors by cardiomyocytes in response to changes in homeostasis, stress, and damage.

—from Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart, a book by Jonathan C. Schisler, Charles H Lang, Monte Willis

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